Chemistry of Roxicodone
The chemical formula of Roxicodone is “(5R,9R,13S,14S)-4,5α-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one”. The molecular weight of this drug has been calculated to be 315.364 g/mol and the purity of this substance in its purest forms has been calculated to be approximately equal to or greater than 99.8% while the total impurities in most cases in less than or equal to 0.2%.
The recommended storage temperature for the drugs is either room temperature or between 20oC to 25oC. In order to keep the drug preserved for a long period of time, it is advised to keep the drug at low temperature of – 20oC while the stability of the molecule of this drug is known to be equal to or greater than two to three years. The chemical formulas of Roxicodone is C18H21NO4.
Usage of Roxicodone
The tablets are an immediate release oral formulation of oxycodone HCL indicated for treating mild to severe pain in the circumstance where the use of an opioid analgesic is appropriate.
Dosage and administration
Roxicodone dosage should be individually adjusted according to patient’s size, patient’s response and how severe the pain is. If the pain is more severe, tolerance occurs, or analgesia is inadequate a gradual increase may be needed.
Patients new to Roxicodone or opioid analgesics should start on a dosage of 5-15 mg every 4-6 hours as required for pain. The dose is titrated following the individual patient’s response to their initial treatment. Patients suffering from chronic pain should receive their dosage on around the clock basis to prevent reappearing of pain rather than treating the pain as it happens. The dose can then be adjusted to an acceptable level putting into considerations the side effects and the reaction of the patient to the drug.
In a bid to control severe pain, patients should take Roxicodone on a regularly scheduled basis, every 4-6 hours, at the lowest level that will achieve adequate analgesia. Just like most potent opioids, it is crucial to adjust the dosing regimen for each patient individually considering his/her previous treatment response.
Although it is impossible to list each condition that is crucial to the selection of the first Roxicodone dose, below are some things to give attention to
Patient’s degree of tolerance to opioids
The patient’s general condition and medical status
Reliability of relative potency estimate to know the dose needed
Potency, daily dose, and characteristics of mixed/pure agonist the patient has been taking
Balance between adverse experiences and pain control
Tablets of Roxicodone
Each tablet contains 5mg, 15mg, and 30mg of oxycodone hydrochloride to be administered orally. It is an odorless, white crystalline powder derived from the opium alkaloid, thebaine. Roxicodone dissolves in water, and it is slightly soluble in alcohol.
The 5mg Roxicodone tablet contains inactive ingredients stearic acid and microcrystalline cellulose. In addition, the 15 and 30 mg tablets also contain the following inactive ingredients: D&C Yellow No. 10 (15 mg tablet), FD&C Blue No. 2 (15 mg and 30 mg tablets), sodium starch glycolate, lactose, and cornstarch. There is oxycodone freebase of 4.6mg, 13.5mg, and 27.0mg in the 5mg, 15mg, and 30 mg tablets respectively.
Roxicodone side effects
Users are likely to experience the following reactions: difficulty breathing, hives, swelling of face tongue, throat, and lips. You should get medical help when you start noticing them. Other effects that you should be aware of include severe weakness, feeling of passing out, shallow breathing, seizure, confusion, and cold/clammy skin. Quit taking Roxicodone and call your doctor when you notice any of these.
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